北京儿童医院

营养与发育研究室
2023-01-29 09:46:48
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Ding X, Liao FF, Su L, Yang X, Yang W, Ren QH, Zhang JZ, Wang HM. Sciatic nerve block downregulates the BDNF pathway to alleviate the neonatal incision-induced exaggeration of incisional pain via decreasing microglial activation. Brain Behav Immun. 2022 Oct;105:204-224. doi: 10.1016/j.bbi.2022.07.010. Epub 2022 Jul 16. PMID: 35853558.

Li P, Chang X, Chen X, Wang C, Shang Y, Zheng D, Qi K. Early-life antibiotic exposure increases the risk of childhood overweight and obesity in relation to dysbiosis of gut microbiota: a birth cohort study. Ann Clin Microbiol Antimicrob. 2022 Nov 3;21(1):46. doi: 10.1186/s12941-022-00535-1. PMID: 36329476; PMCID: PMC9635112.

Liu X, Shi Q, Fan X, Chen H, Chen N, Zhao Y, Qi K. Associations of Maternal Polyunsaturated Fatty Acids With Telomere Length in the Cord Blood and Placenta in Chinese Population. Front Nutr. 2022 Jan 28;8:779306. doi: 10.3389/fnut.2021.779306. PMID: 35155512; PMCID: PMC8831827.

Li M, Shi Q, Jiang X, Liu X, Han W, Fan X, Li P, Qi K. Paternal preconceptional diet enriched with n-3 polyunsaturated fatty acids affects offspring brain function in mice. Front Nutr. 2022 Oct 28;9:969848. doi: 10.3389/fnut.2022.969848. PMID: 36386900; PMCID: PMC9650249.

Shi Q, Liu X, Fan X, Wang R, Qi K. Paternal dietary ratio of n-6: n-3 polyunsaturated fatty acids programs offspring leptin expression and gene imprinting in mice. Front Nutr. 2022 Dec 23;9:1043876. doi: 10.3389/fnut.2022.1043876. PMID: 36618698; PMCID: PMC9816484.

Wang R, Fan X, Lu Y, Chen D, Zhao Y, Qi K. Dietary acetic acid suppress high-fat diet-induced obesity in mice by altering taurine conjugated bile acids metabolism. Curr Res Food Sci. 2022 Oct 19;5:1976-1984. doi: 10.1016/j.crfs.2022.10.021. PMID: 36312883; PMCID: PMC9596597.

Luo Z, He H, Tang T, Zhou J, Li H, Seeram NP, Li D, Zhang K, Ma H, Wu P. Synthesis and Biological Evaluations of Betulinic Acid Derivatives With Inhibitory Activity on Hyaluronidase and Anti-Inflammatory Effects Against Hyaluronic Acid Fragment Induced Inflammation. Front Chem. 2022 May 4;10:892554. doi: 10.3389/fchem.2022.892554. PMID: 35601554; PMCID: PMC9115581.

Li P, Wang Y, Li P, Liu YL, Liu WJ, Chen XY, Tang TT, Qi KM, Zhang Y. Maternal inappropriate calcium intake aggravates dietary-induced obesity in male offspring by affecting the differentiation potential of mesenchymal stem cells. World J Stem Cells. 2022 Oct 26;14(10):756-776. doi: 10.4252/wjsc.v14.i10.756. PMID: 36337156; PMCID: PMC9630989.

Chen S, Yang M, Wang R, Fan X, Tang T, Li P, Zhou X, Qi K. Suppression of high-fat-diet-induced obesity in mice by dietary folic acid supplementation is linked to changes in gut microbiota. Eur J Nutr. 2022 Jun;61(4):2015-2031. doi: 10.1007/s00394-021-02769-9. Epub 2022 Jan 6. PMID: 34993642.

Li P, Chen Y, Song J, Yan L, Tang T, Wang R, Fan X, Zhao Y, Qi K. Maternal DHA-rich n-3 PUFAs supplementation interacts with FADS genotypes to influence the profiles of PUFAs in the colostrum among Chinese Han population: a birth cohort study. Nutr Metab (Lond). 2022 Jul 23;19(1):48. doi: 10.1186/s12986-022-00683-3. PMID: 35871074; PMCID: PMC9308251.

Li P, Chang X, Chen X, Tang T, Liu Y, Shang Y, Qi K. Dynamic colonization of gut microbiota and its influencing factors among the breast-feeding infants during the first two years of life. J Microbiol. 2022 Aug;60(8):780-794. doi: 10.1007/s12275-022-1641-y. Epub 2022 May 27. PMID: 35622224.

Yang R, Ding H, Shan J, Li X, Zhang J, Liu G, Zheng H, Su Y, Yao H, Qi K. Association of fish oil containing lipid emulsions with retinopathy of prematurity: a retrospective observational study. BMC Pediatr. 2022 Mar 2;22(1):113. doi: 10.1186/s12887-022-03174-9. PMID: 35236316; PMCID: PMC8889774.

Tang T, Li P, Zhou X, Wang R, Fan X,Yang M and Qi K*. The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3. Front Immunol. 2021 Aug 26;12:741839. doi: 10.3389/fimmu.2021.741839. eCollection 2021.

Wang R, Chen D*, Wang F, Fan X, Fan C, Tang T, Li P, Yang M, Zhao Y, Qi K*. An insight into the exploration of proliferation of antibiotic resistance genes in high-fat diet induced obesity mice. Genomics. 2021 Jul;113(4):2503-2512. doi: 10.1016/j.ygeno.2021.05.041.

Wang R, Li S, Chen D*, Zhao Y, Wu Y, Qi K*. Selective extraction and enhanced-sensitivity detection of fluoroquinolones in swine body fluids by liquid chromatography-high resolution mass spectrometry: Application in long-term monitoring in livestock. Food Chem. 2021 Mar 30;341(Pt 2):128269. doi: 10.1016/j.foodchem.2020.128269.

Mengyi Y, Ruirui S, Pujuan D, Yuzhuo Y, Wenjuan W, Jun-Jie Gogo L*, Chunlai C*. Nonspecific interactions between SpCas9 and dsDNA sites located downstream of the PAM mediate facilitated diffusion to accelerate target search. 2021 August 20, 12: 12776-12784. DOI: 10.1039/d1sc02633j

Li P#, Li P#, Liu Y, Liu W, Zha L, Chen X, Zheng R, Qi K*, Zhang Y. Maternal vitamin D deficiency increases the risk of obesity in male offspring mice by affecting the immune response. Nutrition. Jul-Aug 2021;87-88:111191. doi: 10.1016/j.nut.2021.111191.

Li P, Yan K, Chang X, Chen X, Wang R, Fan X, Tang T, Zhan D, Qi K*. Sex-specific maternal calcium requirements for the prevention of nonalcoholic fatty liver disease by altering the intestinal microbiota and lipid metabolism in the high-fat-diet-fed offspring mice. Gut Microbes. 2020; 11(6):1590-1607.

Yao H, Fan C, Lu Y, Fan X, Xia L, Li P, Wang R, Tang T, Wang Y, Qi K*. Alteration of gut microbiota affects expression of adiponectin and resistin through modifying DNA methylation in high-fat diet induced obese mice. Genes and Nutrition. 2020;15(1):12.

Yao H, Fan C, Fan X, Lu Y, Wang Y, Wang R, Tang T, Qi K*. Effects of gut microbiota on leptin expression and body weight are lessened by high-fat diet in mice.  Br J Nutr. 2020;124(4):396-406.

Li P, Chen X, Chang X, Tang T, Qi K*. A preliminary study on the differential expression of long noncoding RNAs and messenger RNAs in obese and control mice. J Cell Biochem. 2020;121(2):1126-1143.

Chang X, Li P, Yan K, Lu Y, Tang T, Fan X, Fan C, Zhan D, Qi K*. Maternal dietary calcium status during pregnancy and lactation affects brain DHA accretion through modifying DNA methylation of fatty acid desaturases in the mouse offspring. Nutr Res. 2019;65:29-42.

Qi K. Challenges in Early Childhood development. JAMA Pediatr. 2019;173(4):307-308.

Wang R, Feng F, Chai Y, Meng X, Sui Q, Chen M, Wei Y*, Qi K*. Screening and quantitation of residual antibiotics in two different swine wastewater treatment systems during warm and cold seasons. Sci Total Environ. 2019;660:1542-1554.

Li P, Tang T, Chang X, Fan X, Chen X, Wang R, Fan C, Qi K*. Abnormality in Maternal Dietary Calcium Intake During Pregnancy and Lactation Promotes Body WEIGHT gain by Affecting the Gut Microbiota in Mouse Offspring. Mol Nutr Food Res. 2019; 63(5): 1800399(1-13).

Li P#, Chang X#, Fan X, Fan C, Tang T, Wang R, Qi K*. Dietary calcium status during maternal pregnancy and lactation affects lipid metabolism in mouse offspring. Sci Rep. 2018;8(1):16542.

Lu Y#, Fan C#, Liang A, Fan X, Wang R, Li P, Qi K*. Effects of SCFA on the DNA methylation pattern of adiponectin and resistin in high-fat-diet-induced obese male mice. Br J Nutr. 2018;120(4):385-392.

Lu Y, Fan C, Li P, Lu Y, Chang X, Qi K*. Short Chain Fatty Acids Prevent High-fat-diet-induced Obesity in Mice by Regulating G Protein-coupled Receptors and Gut Microbiota. Sci Rep.2016;37589: 1-13.

Li P, Fan C, Lu Y, Qi K*. Effects of Calcium Supplementation on the Body Weight: A Meta-Analysis. Am J Clin Nutr.2016; 104(5):1263-1273.

Fan C#, Fu H#, Dong H, Lu Y, Lu Y, Qi K*. Maternal n-3 polyunsaturated fatty acid deprivation during pregnancy and lactation affects neurogenesis and apoptosis in adult offspring: associated with DNA methylation of brain-derived neurotrophic factor transcripts. Nutr Res. 2016; 36: 1013-1021.

Fan C, Sun W, Dong H, Fu H, Xia L, Lu Y, Deckelbaum RJ and Qi K*. Dietary ratios of n-6/n-3 polyunsaturated fatty acids during maternal pregnancy and lactation affect hippocampal neurogenesis and apoptosis in mouse offspring. Nutr. Hosp. 2015; 32(3): 1170-1179.

Ding X#, Zheng D#, Fan C, Liu Z, Dong H, Lu Y, Qi K*. Genome-wide screen of DNA methylation identifies novel markers in childhood obesity. Gene. 2015; 566: 74-83.

Xia L, Fan C, Dong H, Wang C, Lu Y, Deckelbaum RJ, Qi K*. Particle Size Determines the Effects of the Lipoprotein Lipase on Catabolism of n-3 Triglyceride Rich Particles. Clin Nutr. 2015; 34(4):767-74.

Xia L, Wang C, Lu Y, Fan C, Ding X, Fu H, Qi K Qi K*. Time-specific changes in DNA methyltransferases associated with the leptin promoter during the development of obesity. Nutr. Hosp. 2014; 30(6): 1248-1255.

Fan C#, Dong H#, Shen W, Xia L, Qi K*. Genome-wide screen of promoter methylation identifies novel markers in diet induced obese mice. Nutr. Hosp. 2014; 30(1): 42-52.

Shen W#, Wang C#, Xia L, Fan C, Dong H, Deckelbaum RJ, Qi K.*. Epigenetic modification of the leptin promoter in diet-induced obese mice and the effects of N-3 polyunsaturated fatty acids. Sci Rep. 2014; 4:5282.

Fan C, Zirpoli H, Qi K*. n-3 fatty acids modulate adipose tissue inflammation and oxidative stress. Curr. Opin. Clin. Nutr. Metab. Care. 2013;16(2):124-132.

Fan C#, Liu X#, Shen W, Tian C, Deckelbaum RJ, Qi K*. The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters. Nutri Metab (Lond). 2011;8:31.

Tian C#, Fan C#, Liu X, Xu F, Qi K*. Brain Histological Changes in Young Mice Submitted to Diets with Different Ratios of n-6/n-3 Polyunsaturated Fatty Acids during Maternal Pregnancy and Lactation. Clin Nutr. 2011;30(5): 659-667.

Zhu H#, Fan C#, Xu F, Jiang J, Tian C, Zhang F, Qi K*. Dietary fish oil n-3 PUFAs  and alpha-linolenic acid differently affect brain accretion of DHA and expression of desaturases and SREBP-1 in mice. J Nutri Biochem. 2010;21(10):954-960.

Qi K*, Fan C, Jiang J, Zhu H, Jiao H, Meng Q, Deckelbaum RJ. Omega-3 fatty acid containing diets decrease plasma triglyceride concentrations in mice by reducing endogenous triglyceride synthesis and enhancing the blood clearance of triglyceride-rich particles. Clin Nutr. 2008;27(3): 424-30.

Qi K*, Seo T, Jiang Z, Carpentier YA, and Deckelbaum RJ. Triglycerides in fish oil affect the blood clearance of lipid emulsions containing long- and medium-chain triglycerides in mice. J Nutrition. 2006, 136(11): 2766-2772.

Seo T, Qi K, Chang C, Liu Y, Worgall TS, Ramakrishnan R and Deckelbaum RJ*. Saturated fatrich diet enhances selective uptake of LDL cholesteryl esters in the arterial wall. J Clin Invest. 2005,115(8):2214-22.

Qi K, Seo T, Al-Haideri M, Carpentier YA, and Deckelbaum RJ*. Effects of particle size on blood clearance and tissue uptake of lipid emulsions with different triglyceride compositions. JPEN, J. Parenter. Enter. Nutr. 2003; 27(1): 58-64.

Qi K, Seo T, Al-Haideri M, Worgall TS, Vogel T, Carpentier YA and Deckelbaum RJ*. Omega-3 triglycerides modify blood clearance and tissue targeting pathways of lipid emulsions. Biochemistry 2002; 41(9): 3119-3127.

Qi K, Hall M and Deckelbaum RJ*. Long-chain polyunsaturated fatty acid accretion in brain (review). Curr. Opin. Clin. Nutr. Metab. Care. 2002; 5(2): 133-8.

Seo T, Velez-Carrasco W, Qi K, Hall M, Worgall TS, Johnson RA and Deckelbaum RJ*. Unsaturated fatty acids and modulated by cholesterol content in plasma membrane. Biochemistry 2002; 41(5): 7885-7894.

Qi Kemin, Jiang Zaifang, Ding Zongyi, et al. Cloning of Chinese OB gene and its expression in E.Coli. Chin. Med. J. 2000; 113(1): 44-48. 

 


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